BDBM449846 1,3-dimethyl-5-[3-[2-(trifluoromethoxy)ethyl]benzimidazol-5-yl]pyridin-2-one ::US10703740, Compound 3::US11365186, Compound 3

SMILES Cc1cc(cn(C)c1=O)-c1ccc2ncn(CCOC(F)(F)F)c2c1

InChI Key InChIKey=ZIQXIXDRXBVJFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449846   

TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Epigenetix

US Patent
LigandPNGBDBM449846(1,3-dimethyl-5-[3-[2-(trifluoromethoxy)ethyl]benzi...)
Affinity DataIC50:  310nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM449846(1,3-dimethyl-5-[3-[2-(trifluoromethoxy)ethyl]benzi...)
Affinity DataIC50:  310nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent