BDBM449848 1,3-dimethyl-5-[2-methyl-3-[2-(trifluoromethoxy)ethyl]benzimidazol-5-yl]pyridin-2-one ::US10703740, Compound 5::US11365186, Compound 5

SMILES Cc1nc2ccc(cc2n1CCOC(F)(F)F)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=RGFKQNCZZJVQFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449848   

TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Epigenetix

US Patent
LigandPNGBDBM449848(1,3-dimethyl-5-[2-methyl-3-[2-(trifluoromethoxy)et...)
Affinity DataIC50:  190nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM449848(1,3-dimethyl-5-[2-methyl-3-[2-(trifluoromethoxy)et...)
Affinity DataIC50:  190nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent