BDBM450377 1-{2,6-dichloro-4-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]phenyl}-3-{[5-(trifluoromethyl)-2-pyridinyl]methyl}urea::US10676438, Example 32
SMILES O[C@H](c1cc(Cl)c(NC(=O)NCc2ccc(cn2)C(F)(F)F)c(Cl)c1)C(F)(F)F
InChI Key InChIKey=XKAKAEMIPHQYGG-CYBMUJFWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 450377
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair