BDBM450827 US10676469, Compound 85::US11124504, Cpd. No. 85

SMILES Cc1nc(no1)-c1c(C)c2cc(OC(F)(F)F)cc(C#N)c2nc1N1CCC(CC1)NC1CCOCC1

InChI Key InChIKey=TYDNPLBGUHADPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450827   

TargetMu-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450827(US10676469, Compound 85 | US11124504, Cpd. No. 85)
Affinity DataIC50: >1.00E+3nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450827(US10676469, Compound 85 | US11124504, Cpd. No. 85)
Affinity DataIC50: >100nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent