BDBM450965 US10676469, Compound 247::US11124504, Cpd. No. 247

SMILES C[C@@H]1C[C@@H](CCN1c1nc2c(cc(C)cc2c(C)c1-c1nc(C)no1)C#N)NC[C@@H]1CCCO1

InChI Key InChIKey=XRIRFXFWISMBBN-HBGVWJBISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450965   

TargetMu-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450965(US10676469, Compound 247 | US11124504, Cpd. No. 24...)
Affinity DataIC50:  55nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450965(US10676469, Compound 247 | US11124504, Cpd. No. 24...)
Affinity DataIC50: <1nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent