BDBM450972 US10676469, Compound 254::US11124504, Cpd. No. 254

SMILES COc1cc(C#N)c2nc(N3CCC(CC3)N[C@@H]3CCOC3)c(cc2c1)-c1nc(C)no1

InChI Key InChIKey=RLDOBTLGCYDLCC-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450972   

TargetMu-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450972(US10676469, Compound 254 | US11124504, Cpd. No. 25...)
Affinity DataIC50: >1.00E+3nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450972(US10676469, Compound 254 | US11124504, Cpd. No. 25...)
Affinity DataIC50: >100nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent