BDBM452817 6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicyclo[3.1.0]hexan- 6-yl)-1,2,4-oxadiazol- 5-yl)methyl)-1-methyl- 1,6-dihydro-7H- [1,2,3]triazolo[4,5-d]::US10711004, Example 139
SMILES Cn1nnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CN(C[C@@H]34)c3cccc(Cl)c3)c(=O)c12
InChI Key InChIKey=ZIKZMIAHXLHIRK-NHAGDIPZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 452817
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 3.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 10.6nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair