BDBM452817 6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicyclo[3.1.0]hexan- 6-yl)-1,2,4-oxadiazol- 5-yl)methyl)-1-methyl- 1,6-dihydro-7H- [1,2,3]triazolo[4,5-d]::US10711004, Example 139

SMILES Cn1nnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CN(C[C@@H]34)c3cccc(Cl)c3)c(=O)c12

InChI Key InChIKey=ZIKZMIAHXLHIRK-NHAGDIPZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452817   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452817(6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicycl...)
Affinity DataIC50:  3.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452817(6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicycl...)
Affinity DataIC50:  10.6nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent