BDBM452891 6-((3-((1R,5S,6r)-3- phenyl-3-azabicyclo [3.1.0]hexan-6-yl)- 1,2,4-oxadiazol-5-yl) methyl)pyrido[2,3-d] pyridazin-5(6H)-one::US10711004, Example 213

SMILES O=c1n(Cc2nc(no2)[C@@H]2[C@H]3CN(C[C@@H]23)c2ccccc2)ncc2ncccc12

InChI Key InChIKey=RQQAWKCHVMJSHO-MNZLEMJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452891   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452891(6-((3-((1R,5S,6r)-3- phenyl-3-azabicyclo [3.1.0]he...)
Affinity DataIC50:  5.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM452891(6-((3-((1R,5S,6r)-3- phenyl-3-azabicyclo [3.1.0]he...)
Affinity DataIC50:  6.17nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent