BDBM452891 6-((3-((1R,5S,6r)-3- phenyl-3-azabicyclo [3.1.0]hexan-6-yl)- 1,2,4-oxadiazol-5-yl) methyl)pyrido[2,3-d] pyridazin-5(6H)-one::US10711004, Example 213
SMILES O=c1n(Cc2nc(no2)[C@@H]2[C@H]3CN(C[C@@H]23)c2ccccc2)ncc2ncccc12
InChI Key InChIKey=RQQAWKCHVMJSHO-MNZLEMJZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 452891
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 5.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 6.17nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair