BDBM453270 2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acetyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenoxy)-N-(pentan-3-yl)acetamide::US10729691, Example 55

SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C(C)=O

InChI Key InChIKey=BERIUAAWZMNNJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453270   

TargetPutative sugar transporter(Plasmodium falciparum)
Kadmon

US Patent
LigandPNGBDBM453270(2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acety...)
Affinity DataIC50:  55nMAssay Description:Parasite cultures were seeded in 96-well plates (1% hematocrit, 1-2% starting parasitemia, 100 μL total volume) with varying concentrations of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 2, facilitated glucose transporter member 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM453270(2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acety...)
Affinity DataIC50:  55nMAssay Description:HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent