BDBM453271 2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acetyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenoxy)-N-(tert-butyl)acetamide::US10729691, Example 56
SMILES CC(=O)N1Cc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1
InChI Key InChIKey=UXUXSHHSBBCWMB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 453271
Affinity DataIC50: 175nMAssay Description:Parasite cultures were seeded in 96-well plates (1% hematocrit, 1-2% starting parasitemia, 100 μL total volume) with varying concentrations of t...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 1(Homo sapiens (Human))
Kadmon
US Patent
Kadmon
US Patent
Affinity DataIC50: 55nMAssay Description:HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...More data for this Ligand-Target Pair