BDBM454354 US10717734, Compound 30

SMILES Cc1c(Cc2ccc(nc2)S(C)(=O)=O)c2nc(ccc2n1C\C(F)=C\CN)C(C)(F)F

InChI Key InChIKey=NKZJFBGESYRVGV-NVNXTCNLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 454354   

TargetOxidized low-density lipoprotein receptor 1(Bovine)
Pharmaxis

US Patent
LigandPNGBDBM454354(US10717734, Compound 30)
Affinity DataIC50: >3.00E+5nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Pharmaxis

US Patent
LigandPNGBDBM454354(US10717734, Compound 30)
Affinity DataIC50: >3.00E+3nMAssay Description:MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Pharmaxis

US Patent
LigandPNGBDBM454354(US10717734, Compound 30)
Affinity DataIC50: >3.00E+3nMAssay Description:SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

US Patent
LigandPNGBDBM454354(US10717734, Compound 30)
Affinity DataIC50: <3.00E+5nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent