BDBM455309 US10730875, Compound 9

SMILES O[C@@H]1CCN(Cc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)cn23)C1

InChI Key InChIKey=UKBDRKYMJJIFAT-GOSISDBHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 455309   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455309(US10730875, Compound 9)
Affinity DataIC50:  3.00E+3nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455309(US10730875, Compound 9)
Affinity DataIC50: >5.00E+3nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455309(US10730875, Compound 9)
Affinity DataIC50: >5.00E+3nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455309(US10730875, Compound 9)
Affinity DataIC50: >5.00E+3nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent