BDBM456056 US10723709, Reference Example 9::US11312693, Ref Ex 9

SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-c1ccc(cc1)-c1csc(n1)-[#7]-1-[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](\[#6]=[#6](/Br)Br)-[#6@H]-2-[#8]-[#6]-[#6](=O)-[#6@@H]-1-2

InChI Key InChIKey=FMIOWRCJJNGGIF-WSAILGMDSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 456056   

TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  2.60nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  2.60nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  6.10E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM456056(US10723709, Reference Example 9 | US11312693, Ref ...)
Affinity DataKi:  6.10E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent