BDBM456059 US10723723, Example 1-I::US10723723, Example 1-II
SMILES CN(CC(O)c1ccc2C(=O)OCc2c1C)Cc1ccc(nc1)-c1ccc2oc(=O)n(C)c2c1
InChI Key InChIKey=JLKKVVRWYNGDOE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 456059
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 19nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2), 1 Mg...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 830nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 170nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair