BDBM458097 Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(4-isobutyl-7-(4-methylbenzyl)-2,3-dihydro-1H-indene-5-yl)tetrahydro-2H-pyran-3,4,5-triol::US10752604, Example 64

SMILES CC(C)Cc1c2CCCc2c(Cc2ccc(C)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=XPTULWONZFXGRE-SEFGFODJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458097   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458097(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50:  19.1nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458097(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50:  518nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent