BDBM458603 US10745401, Example 77::US11466007, Example 77

SMILES CC1CN(CCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2cnn(C)c12

InChI Key InChIKey=IQVLUGMPXUFAHZ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 458603   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458603(US10745401, Example 77 | US11466007, Example 77)
Affinity DataKi:  0.240nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458603(US10745401, Example 77 | US11466007, Example 77)
Affinity DataKi:  0.240nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458603(US10745401, Example 77 | US11466007, Example 77)
Affinity DataKi:  0.960nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458603(US10745401, Example 77 | US11466007, Example 77)
Affinity DataKi:  0.960nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458603(US10745401, Example 77 | US11466007, Example 77)
Affinity DataKi:  605nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458603(US10745401, Example 77 | US11466007, Example 77)
Affinity DataKi:  605nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent