BDBM458718 5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]ethyl}-6,7-dihydro[1,3]imidazolo[4,5-c]pyridin-4(5H)-one::US10745401, Example 191::US11466007, Example 191

SMILES O=C1N(CCN2CCC(CC2)c2noc3ccccc23)CCc2[nH]cnc12

InChI Key InChIKey=BAIXKGAZCOGILC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 458718   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458718(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.340nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458718(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458718(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  286nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458718(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  286nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458718(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  817nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458718(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  817nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent