BDBM45885 3-(1-imidazolylmethyl)pyridine::3-(imidazol-1-ylmethyl)pyridine::MLS-0091918.0001::US9394290, 3::cid_16654684

SMILES C(c1cccnc1)n1ccnc1

InChI Key InChIKey=IRLWEKCRDMFHQW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 45885   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM45885(3-(1-imidazolylmethyl)pyridine | 3-(imidazol-1-ylm...)
Affinity DataIC50: >1.00E+5nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCytochrome P450 2A6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM45885(3-(1-imidazolylmethyl)pyridine | 3-(imidazol-1-ylm...)
Affinity DataIC50: >2.00E+5nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM45885(3-(1-imidazolylmethyl)pyridine | 3-(imidazol-1-ylm...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM45885(3-(1-imidazolylmethyl)pyridine | 3-(imidazol-1-ylm...)
Affinity DataIC50: >1.00E+3nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM45885(3-(1-imidazolylmethyl)pyridine | 3-(imidazol-1-ylm...)
Affinity DataIC50:  816nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM45885(3-(1-imidazolylmethyl)pyridine | 3-(imidazol-1-ylm...)
Affinity DataIC50:  816nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent