BDBM458880 US10759793, Example 32
SMILES OCC(=O)N1CCC[C@H](C1)Nc1nc(nc(-c2cn[nH]c2)c1F)-c1cnn2ccccc12
InChI Key InChIKey=IILSYWHBZRJVTF-CQSZACIVSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 458880
Affinity DataIC50: 4nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair