BDBM461317 US10774068, Example 22::US11427560, Example 22

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4C)c(F)c3)c2cc1NC(=O)CCCN(C)C

InChI Key InChIKey=ABGGVUAOCXKIPW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 461317   

TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461317(US10774068, Example 22 | US11427560, Example 22)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461317(US10774068, Example 22 | US11427560, Example 22)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461317(US10774068, Example 22 | US11427560, Example 22)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461317(US10774068, Example 22 | US11427560, Example 22)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent