BDBM463283 5-(4-Chloro-3-hydroxy- phenyl)-5-methyl-2-(8- (3,3,4,4,4-pentafluoro- butyl)-[1,2,4]triazolo- [1,5-a]pyrazin-6-yl)-4- [(3,3,3-trifluoro-2- hydroxypropyl)amino]- 5,7-dihydro-6H-pyrrolo- [2,3-d]pyrimidin-6-one::US10780092, Example 133-AA::US10780092, Example 133-AB
SMILES CC1(C(=O)Nc2nc(nc(NCC(O)C(F)(F)F)c12)-c1cn2ncnc2c(CCC(F)(F)C(F)(F)F)n1)c1ccc(Cl)c(O)c1
InChI Key InChIKey=KYIBDNDGOPSVQG-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 463283
Affinity DataKi: 2.34nMAssay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair
Affinity DataKi: 9.24nMAssay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair