BDBM463432 3-amino-N-[(3R)-1-[(3-chlorophenyl)methyl]pyrrolidin-3-yl]-1-({4-[(2-oxopyridin-1-::US10781181, Example 108
SMILES Nc1nn(Cc2ccc(Cn3ccccc3=O)cc2)cc1C(=O)N[C@@H]1CCN(Cc2cccc(Cl)c2)C1
InChI Key InChIKey=AZEWSURGSXDQEJ-XMMPIXPASA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 463432
Affinity DataIC50: >4.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods. Human KLK1 (Callbiochem) was incubated at 25° C. with the fluoroge...More data for this Ligand-Target Pair
Affinity DataIC50: 299nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods. Human plasma kallikrein (Protogen) was incubated at 2...More data for this Ligand-Target Pair