BDBM463561 (2S)-3-[(3S,4S)- 3-[(1R)-1- hydroxyethyl]-4- (4-methoxy-3- {[1-(5- cyanopyridin-2- yl)azetidin-3- yl]oxy}phenyl)- 3- methylpyrrolidin- 1-yl]-3- oxopropane-1,2-::US10781202, Example 6

SMILES COc1ccc(cc1OC1CN(C1)c1ccc(cn1)C#N)[C@@H]1CN(C[C@@]1(C)[C@@H](C)O)C(=O)[C@@H](O)CO

InChI Key InChIKey=RIMCISMKSOSZMT-JLUIAWOOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463561   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM463561((2S)-3-[(3S,4S)- 3-[(1R)-1- hydroxyethyl]-4- (4-me...)
Affinity DataIC50:  0.310nMAssay Description: PDE4A, PDE4B, PDE4C, PDE4D, and PDE5 human recombinant proteins are expressed and purified from Saccharomyes cerevisiae that lack endogenous PDEs. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent