BDBM464262 3-(4-(1H-pyrazol-4- yl)phenyl)-1-(3- fluoro-2- methylbenzyl)-8-(2- hydroxyethyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 143
SMILES Cc1c(F)cccc1CN1C(=O)N(CC11CCN(CCO)CC1)c1ccc(cc1)-c1cn[nH]c1
InChI Key InChIKey=MRLHWLRQPXUJJR-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464262
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair