BDBM464283 1-(3-fluoro-2- methylbenzyl)-3-(6- methoxy-5-(1H- pyrazol-4-yl)pyridin- 2-yl)-8-(2- methoxyethyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 165
SMILES COCCN1CCC2(CN(C(=O)N2Cc2cccc(F)c2C)c2ccc(-c3cn[nH]c3)c(OC)n2)CC1
InChI Key InChIKey=FYPVFLFALNIHBL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464283
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair