BDBM464283 1-(3-fluoro-2- methylbenzyl)-3-(6- methoxy-5-(1H- pyrazol-4-yl)pyridin- 2-yl)-8-(2- methoxyethyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 165

SMILES COCCN1CCC2(CN(C(=O)N2Cc2cccc(F)c2C)c2ccc(-c3cn[nH]c3)c(OC)n2)CC1

InChI Key InChIKey=FYPVFLFALNIHBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464283   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM464283(1-(3-fluoro-2- methylbenzyl)-3-(6- methoxy-5-(1H- ...)
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent