BDBM464286 Preparation of 2-(3-(4-(1H-pyrazol-4-yl)phenyl)-1-(3-methoxybenzyl)-2-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)-N-methylacetamide::US10787450, Example 168
SMILES CNC(=O)CN1CCC2(CN(C(=O)N2Cc2cccc(OC)c2)c2ccc(cc2)-c2cn[nH]c2)CC1
InChI Key InChIKey=OOZRFCRBNSPYQA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464286
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair