BDBM464291 3-(4-(1H-pyrazol-4- yl)phenyl)-1-(3- methoxybenzyl)-8- (tetrahydro-2H-pyran- 4-carbonyl)-1,3,8- triazaspiro[4.5]decan- 2-one, TFA::US10787450, Example 173
SMILES COc1cccc(CN2C(=O)N(CC22CCN(CC2)C(=O)C2CCOCC2)c2ccc(cc2)-c2cn[nH]c2)c1
InChI Key InChIKey=IBBSFSGUMBZFHB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464291
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair