BDBM464348 1-(3-fluoro-2- methylbenzyl)-8-(2- hydroxy-2- methylpropanoyl)-3- (6-methoxy-5-(1H- pyrazol-4-yl)pyridin- 2-yl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 230
SMILES COc1nc(ccc1-c1cn[nH]c1)N1CC2(CCN(CC2)C(=O)C(C)(C)O)N(Cc2cccc(F)c2C)C1=O
InChI Key InChIKey=COODZZHINRCXRT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464348
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair