BDBM464349 Preparation of 3-(4-(1H-pyrazol-4-yl)phenyl)-8-((4,4-difluorocyclohexyl)methyl)-1-(3-methoxybenzyl)-1,3,8-triazaspiro[4.5]decan-2-one::US10787450, Example 231
SMILES COc1cccc(CN2C(=O)N(CC22CCN(CC3CCC(F)(F)CC3)CC2)c2ccc(cc2)-c2cn[nH]c2)c1
InChI Key InChIKey=BBHSJBWSVZIKFI-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464349
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair