BDBM464350 3-(4-(1H- pyrazol-4- yl)phenyl)-8- (cyclobutyl- methyl)-1- (3-methoxy- benzyl)- 1,3,8- triazaspiro [4.5]decan- 2-one::US10787450, Example 232
SMILES COc1cccc(CN2C(=O)N(CC22CCN(CC3CCC3)CC2)c2ccc(cc2)-c2cn[nH]c2)c1
InChI Key InChIKey=HMWCDFAGWWKYPR-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464350
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair