BDBM464351 3-(4-(1H- pyrazol-4- yl)phenyl)-1-(3- methoxy- benzyl)-8- ((tetrahydro-2H- pyran-4- yl)methyl)- 1,3,8- triazaspiro::US10787450, Example 233

SMILES COc1cccc(CN2C(=O)N(CC22CCN(CC3CCOCC3)CC2)c2ccc(cc2)-c2cn[nH]c2)c1

InChI Key InChIKey=KLROLIVQJLATTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464351   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM464351(3-(4-(1H- pyrazol-4- yl)phenyl)-1-(3- methoxy- ben...)
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent