BDBM464357 1-(3-fluoro-2- methyl- benzyl)-3-(6- methoxy-5- (1H-pyrazol-4- yl)pyridin- 2-yl)-8- (oxetan-3-yl)- 1,3,8- triazaspiro [4.5]decan- 2-one::US10787450, Example 239
SMILES COc1nc(ccc1-c1cn[nH]c1)N1CC2(CCN(CC2)C2COC2)N(Cc2cccc(F)c2C)C1=O
InChI Key InChIKey=LWKAIIXDOOPNFY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464357
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair