BDBM464591 CIS-8-Dimethylamino-1-[(1-hydroxy-cyclobutyl)-methyl]-3-(2-methylsulfonyl- ethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one::US10793556, Example SC_4011

SMILES CN(C)[C@]1(CC[C@]2(CN(CCS(C)(=O)=O)C(=O)N2CC2(O)CCC2)CC1)c1ccccc1

InChI Key InChIKey=SMVBNPIXERKTKH-QUPDYRNUSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 464591   

TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464591(CIS-8-Dimethylamino-1-[(1-hydroxy-cyclobutyl)-meth...)
Affinity DataKi:  13nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464591(CIS-8-Dimethylamino-1-[(1-hydroxy-cyclobutyl)-meth...)
Affinity DataKi:  210nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent