BDBM464667 CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-(3-fluorophenyl)-3-[(4-hydroxy- tetrahydro-pyran-4-yl)-methyl]-1,3-diazaspiro[4.5]decan-2-one::US10793556, Example SC_4094::US10793556, Example SC_4095

SMILES CN(C)[C@]1(CC[C@]2(CN(C3CCN(CC3)c3cncnc3)C(=O)N2CC2(O)CCC2)CC1)c1ccccc1

InChI Key InChIKey=IEWPWVIQANENFH-KRKINAOUSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 464667   

TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464667(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-(3-fl...)
Affinity DataKi:  8nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464667(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-(3-fl...)
Affinity DataKi:  23nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464667(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-(3-fl...)
Affinity DataKi:  630nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464667(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-(3-fl...)
Affinity DataKi:  1.98E+3nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent