BDBM464669 CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-phenyl-3-(1-pyridazin-4-yl- pipendrin-4-yl)-1,3-diazaspiro[4.5]decan-2-one::US10793556, Example SC_4096::US10793556, Example SC_4097::US10793556, Example SC_4098

SMILES CN(C)[C@]1(CC[C@]2(CN(CC3(O)CCS(=O)(=O)CC3)C(=O)N2CC2(O)CCC2)CC1)c1cccc(F)c1

InChI Key InChIKey=KISPODHBALDJRI-FEGDYQJNSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 464669   

TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464669(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-pheny...)
Affinity DataKi:  36nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464669(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-pheny...)
Affinity DataKi:  96nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464669(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-pheny...)
Affinity DataKi:  114nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464669(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-pheny...)
Affinity DataKi:  330nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464669(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-pheny...)
Affinity DataKi:  395nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464669(CIS-1-(Cyclopropyl-methyl)-8-dimethylamino-8-pheny...)
Affinity DataKi:  4.36E+3nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent