BDBM465380 US10793567, Compound 16::US11225479, Compound 16

SMILES Nc1ccc(nc1NC(=O)N1Cc2cnc(cc2C1)C(F)F)-c1cccnc1

InChI Key InChIKey=IODXLLVFYQYBMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 465380   

TargetHistone deacetylase 2(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM465380(US10793567, Compound 16 | US11225479, Compound 16)
Affinity DataIC50: >1.50E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465380(US10793567, Compound 16 | US11225479, Compound 16)
Affinity DataIC50:  2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM465380(US10793567, Compound 16 | US11225479, Compound 16)
Affinity DataIC50:  2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465380(US10793567, Compound 16 | US11225479, Compound 16)
Affinity DataIC50: >1.50E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent