BDBM465473 US10793568, Compound I-124

SMILES Cc1cccc(Cl)c1-c1noc(c1CO[C@@H]1C[C@@H]2C[C@H]1CN2c1ccc(C(O)=O)c(F)c1)C1(F)CC1

InChI Key InChIKey=QHFVVXOCJGQFOC-GIMINZRKSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465473   

TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465473(US10793568, Compound I-124)
Affinity DataEC50:  0.200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent