BDBM466592 US10800757, Compound 8::US10889568, Compound 8::[7-(6-Amino-4-methoxy-pyridin-3-yl)- 4,7-diaza-spiro[2.5]oct-4-yl]-(4- methoxy-5-phenoxy-pyridin-2-yl)- methanone
SMILES COc1cc(ncc1Oc1ccccc1)C(=O)N1CCN(CC11CC1)c1cnc(N)cc1OC
InChI Key InChIKey=QTMDPULCRGIORS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 466592
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 27nMAssay Description:This screening assay measures TRPC6 (transient receptor potential cation channel, subfamily C, member 6) ion channel activation via addition either o...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 27nMAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC6 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair