BDBM466598 (6-Amino-3',4',5',6'-tetrahydro-2'H- [3,4']bipyridinyl-1'-yl)-[5-(4-fluoro- phenoxy)-4-methoxy-pyridin-2-yl]- methanone::US10800757, Compound 14::US10889568, Compound 14

SMILES COc1cc(ncc1Oc1ccc(F)cc1)C(=O)N1CCC(CC1)c1ccc(N)nc1

InChI Key InChIKey=RLKJVKIBUPJIQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466598   

TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466598((6-Amino-3',4',5',6'-tetrahydro-2'H- [3,4']bipyrid...)
Affinity DataIC50:  27nMAssay Description:This screening assay measures TRPC6 (transient receptor potential cation channel, subfamily C, member 6) ion channel activation via addition either o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466598((6-Amino-3',4',5',6'-tetrahydro-2'H- [3,4']bipyrid...)
Affinity DataIC50:  27nMAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC6 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent