BDBM466634 (1R)-1-[(2R)-4-(6-amino-4- methoxypyridin-3-yl)-1-(5- phenoxypyridine-2- carbonyl)piperazin-2-yl]ethan-1-ol::US10800757, Compound 50::US10889568, Compound 50

SMILES COc1cc(N)ncc1N1CCN([C@H](C1)[C@@H](C)O)C(=O)c1ccc(Oc2ccccc2)cn1

InChI Key InChIKey=ZKJBXFZKZUOFQX-IIBYNOLFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466634   

TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466634((1R)-1-[(2R)-4-(6-amino-4- methoxypyridin-3-yl)-1-...)
Affinity DataIC50:  47nMAssay Description:This screening assay measures TRPC6 (transient receptor potential cation channel, subfamily C, member 6) ion channel activation via addition either o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM466634((1R)-1-[(2R)-4-(6-amino-4- methoxypyridin-3-yl)-1-...)
Affinity DataIC50:  47nMAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC6 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent