BDBM466861 US10800767, Example 14::US10800767, Example 4

SMILES CC(C)c1cc(Oc2c(Cl)cc(NC(=O)c3noc(=O)[nH]3)cc2Cl)nn(C)c1=O

InChI Key InChIKey=WFIWVDVCNWOMQV-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 466861   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466861(US10800767, Example 14 | US10800767, Example 4)
Affinity DataEC50:  27.1nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466861(US10800767, Example 14 | US10800767, Example 4)
Affinity DataEC50:  549nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466861(US10800767, Example 14 | US10800767, Example 4)
Affinity DataEC50:  46.6nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466861(US10800767, Example 14 | US10800767, Example 4)
Affinity DataEC50:  314nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent