BDBM466956 8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3-fluoro-4-methoxyphenyl)- [1,2,4]triazole[4,3-a]pyridine::US10800776, Example 44

SMILES COc1ccc(cc1F)-c1ccn2c(CC3CC3(F)F)nnc2c1Cl

InChI Key InChIKey=IEEMODLUHCUAEF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 466956   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466956(8-chloro-3-((2,2-difluorocyclopropyl) methyl)-7-(3...)
Affinity DataEC50:  118nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent