BDBM467291 7-amino-3-((S)-1-((E)-3-((R)-1-ethylazetidin-2- yl)acryloyl)piperidin-3-yl)-1-(4-(2-fluorophenoxy) phenyl)-1,5-dihydro-4H-pyrrolo[2,3-d]pyridazin- 4-one::US10800785, Example 110

SMILES CCN1CC[C@@H]1\C=C\C(=O)N1CCC[C@H](C1)c1cn(-c2ccc(Oc3ccccc3F)cc2)c2c(N)n[nH]c(=O)c12

InChI Key InChIKey=SJMZNONTCSODCB-HAOIUOIRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 467291   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467291(7-amino-3-((S)-1-((E)-3-((R)-1-ethylazetidin-2- yl...)
Affinity DataIC50:  123nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent