BDBM468371 N,N′-(2-chloro-2′-methylbiphenyl-3,3′-diyl)bis(5-((2-hydroxyethylamino)methyl)picolinamide)::US10806785, Example 11::US11465981, Example 1::US11596692, Compound P7

SMILES Cc1c(NC(=O)c2ccc(CNCCO)cn2)cccc1-c1cccc(NC(=O)c2ccc(CNCCO)cn2)c1Cl

InChI Key InChIKey=XCQYFNZAXNCHOY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 468371   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM468371(N,N′-(2-chloro-2′-methylbiphenyl-3,3&#...)
Affinity DataIC50: <0.100nMAssay Description:Binding assays were conducted in a low volume white 384-well polystyrene plate in a final volume of 20 μL. Compounds to be analyzed were first s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Incyte

US Patent
LigandPNGBDBM468371(N,N′-(2-chloro-2′-methylbiphenyl-3,3&#...)
Affinity DataIC50: <0.100nMAssay Description:Binding assays were conducted in a low volume white 384-well polystyrene plate in a final volume of 20 μL. Compounds to be analyzed were first s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Incyte

US Patent
LigandPNGBDBM468371(N,N′-(2-chloro-2′-methylbiphenyl-3,3&#...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent