BDBM468598 US10807944, Compound RLS2-290::US11731934, Compound RLS2-290

SMILES CCCCNNC(=O)c1ccncc1

InChI Key InChIKey=WESUGDYVVJOCIZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 468598   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468598(US10807944, Compound RLS2-290 | US11731934, Compou...)
Affinity DataIC50:  4.28E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468598(US10807944, Compound RLS2-290 | US11731934, Compou...)
Affinity DataIC50:  1.37E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468598(US10807944, Compound RLS2-290 | US11731934, Compou...)
Affinity DataIC50:  1.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468598(US10807944, Compound RLS2-290 | US11731934, Compou...)
Affinity DataIC50:  4.28E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468598(US10807944, Compound RLS2-290 | US11731934, Compou...)
Affinity DataIC50:  1.37E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468598(US10807944, Compound RLS2-290 | US11731934, Compou...)
Affinity DataIC50:  1.40E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent