BDBM468602 US10807944, Compound RLS2-312::US11731934, Compound RLS2-312

SMILES CCCCNNC(=O)c1ccc(CN=[N+]=[N-])cc1

InChI Key InChIKey=NRJRDICLAPALFB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 468602   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  320nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  527nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  150nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  886nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  320nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  527nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  886nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468602(US10807944, Compound RLS2-312 | US11731934, Compou...)
Affinity DataIC50:  9nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent