BDBM468605 US10807944, Compound RLS3-6::US11731934, Compound RLS3-6

SMILES CCCCNNC(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=AQKWLXUJISFZRN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 468605   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468605(US10807944, Compound RLS3-6 | US11731934, Compound...)
Affinity DataIC50:  3.53E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468605(US10807944, Compound RLS3-6 | US11731934, Compound...)
Affinity DataIC50:  9.33E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468605(US10807944, Compound RLS3-6 | US11731934, Compound...)
Affinity DataIC50:  1.88E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468605(US10807944, Compound RLS3-6 | US11731934, Compound...)
Affinity DataIC50:  3.53E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468605(US10807944, Compound RLS3-6 | US11731934, Compound...)
Affinity DataIC50:  9.33E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468605(US10807944, Compound RLS3-6 | US11731934, Compound...)
Affinity DataIC50:  1.88E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent