BDBM468611 US10807944, Compound SR-4370::US11731934, Compound SR-4370

SMILES CCCCNNC(=O)c1ccc(cc1)-c1cccc(F)c1F

InChI Key InChIKey=OSQKWTZHYXRTBG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 468611   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  130nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  580nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  6nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  2.30E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  3.70E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  130nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  6nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  6nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  2.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  3.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  130nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  580nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM468611(US10807944, Compound SR-4370 | US11731934, Compoun...)
Affinity DataIC50:  580nMMore data for this Ligand-Target Pair
In DepthDetails US Patent