BDBM470062 Racemate of 1-[(4′aS,10′bS)-9′-chloro-5′,5′-dimethyl-4′a,10′b-dihydro-2′H,4′H,5′H-spiro[piperidine-4,3′-pyrano[3,2-c][1]benzopyran]-1-yl]-2-(2-methyl-1H-imidazol-1-yl)ethan-1-one and 1-[(4′aR,10′bR)-9′-chloro-5′,5′-dimethyl-4′a,10′b-dihydro-2′H, 4′H, 5′H-spiro[piperidine-4,3′-pyrano[3,2-c][1]benzopyran]-1-yl]-2-(2-methyl-1H-imidazol-1-yl)ethan-1-one::US10807993, Example 1

SMILES Cc1nccn1CC(=O)N1CCC2(CC1)COC1C(C2)C(C)(C)Oc2ccc(Cl)cc12

InChI Key InChIKey=KUSQHMDFDNXTBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470062   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM470062(Racemate of 1-[(4′aS,10′bS)-9′-c...)
Affinity DataIC50: <300nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent