BDBM470079 Racemate of (4′aR,10′bR)-8′-chloro-5′,5′-dimethyl-1-[(4-methyl-1H-imidazol-5-yl)methyl]-4′a,10′b-dihydro-2′H,4′H,5′H-spiro[piperidine-4,3′-pyrano[3,2-c][1]benzopyran] and (4′aS,10′bS)-8′-chloro-5′,5′-dimethyl-1-[(4-methyl-1H-imidazol-5-yl)methyl]-4′a,10′b-dihydro-2′H,4′H,5′H-spiro[piperidine-4,3′-pyrano[3,2-c][1]benzopyran]::US10807993, Example 18::US10807993, Example 19::US10807993, Example 20
SMILES Cc1nc[nH]c1CN1CC[C@@]2(CC1)COC1C(C2)C(C)(C)Oc2cc(Cl)ccc12
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 470079
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Sumitomo Dainippon Pharma
US Patent
Affinity DataIC50: 600nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Sumitomo Dainippon Pharma
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Sumitomo Dainippon Pharma
US Patent
Affinity DataIC50: 400nMAssay Description:To a cultured CHO cell strain which stably expresses hERG was added each test compound to adjust the final concentration of DMSO to 0.0135 to 0.5%. T...More data for this Ligand-Target Pair